Genetic Characterization of the Factor VIII Gene in a Cohort of Colombian Patients with Severe Hemophilia A with Inhibitors

Genetic Characterization of the Factor VIII Gene in a Cohort of Colombian Patients with Severe Hemophilia A with Inhibitors

Hemophilia A is an X-linked bleeding disorder caused by mutations in the FVIII gene. Genetic factors have been shown to be a risk factor for the development of inhibitors. We aimed to identify the specific variations of the FVIII gene of patients with hemophilia A with inhibitors and their associati...

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Bibliographic Details
Main Authors: Samuel Sarmiento Doncel, Gina Alejandra Diaz Mosquera, Ronald Guillermo Pelaez, Javier Mauricio Cortes, Carol Agudelo Rico, Francisco Javier Meza Cadavid, Nelson Ramirez Plazas, Ivan Alfredo Perdomo Amar, Jorge Enrique Peña Siado, Fabian Andres Parrado Rey, Cesar Alberto Montaño, Alexys Maza Villadiego
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Hematology Reports
Subjects:
factor VIII
hemophilia A
inhibitor
mutation
X chromosome
Online Access:https://www.mdpi.com/2038-8330/14/2/22

Internet

https://www.mdpi.com/2038-8330/14/2/22

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