Structure-based inhibitor design for reshaping bacterial morphology

Structure-based inhibitor design for reshaping bacterial morphology

Peptidoglycan hydrolase 3 (Pgp3) inhibitors are designed that can change the helical morphology of Campylobacter jejuni to rod-shaped and decrease its virulence.

Bibliographic Details
Main Authors: Yuri Choi, Ji Su Park, Jinshil Kim, Kyungjin Min, Kiran Mahasenan, Choon Kim, Hye-Jin Yoon, Sewon Lim, Dae Hee Cheon, Yan Lee, Sangryeol Ryu, Shahriar Mobashery, B. Moon Kim, Hyung Ho Lee
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-022-03355-3

Internet

https://doi.org/10.1038/s42003-022-03355-3

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