HUCMSC‐derived Exosomes Suppress the Titanium Particles‐induced Osteolysis in Mice through Inhibiting CCL2 and CCL3

HUCMSC‐derived Exosomes Suppress the Titanium Particles‐induced Osteolysis in Mice through Inhibiting CCL2 and CCL3

Objective Wear particles induce inflammation and the further osteolysis around the prosthesis, has been proven to be the main cause of aseptic hip joint loosening. In this research, we aimed to clarify whether human umbilical cord mesenchymal stem cells (HUCMSCs) could inhibit the titanium particles...

Full description

Bibliographic Details
Main Authors: Shixun Li, Chuangran Wu, Sipeng Lin, Zhenkang Wen, Wenqiang Luo, Changchuan Li, Xiaoyan Wang, Xuejia Li, Liangbin Gao, Yue Ding
Format: Article
Language:English
Published: Wiley 2023-03-01
Series:Orthopaedic Surgery
Subjects:
Aseptic loosening
CCL2
CCL3
Exosome
HUCMSC
Macrophage
Online Access:https://doi.org/10.1111/os.13608

Internet

https://doi.org/10.1111/os.13608

Similar Items