Selective Targeting of Serotonin 5-HT1a and 5-HT3 Receptors Attenuates Acute and Long-Term Hypersensitivity Associated With Neonatal Procedural Pain

Neonatal painful procedures causes acute pain and trigger long-term changes in nociceptive processing and anxiety behavior, highlighting the need for adequate analgesia during this critical time. Spinal serotonergic receptors 5-HT1a and 5-HT3 play an important role in modulating incoming nociceptive...

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Príomhchruthaitheoirí: Anne R. de Kort, Elbert A. Joosten, Jacob Patijn, Dick Tibboel, Nynke J. van den Hoogen
Formáid: Alt
Teanga:English
Foilsithe / Cruthaithe: Frontiers Media S.A. 2022-04-01
Sraith:Frontiers in Pain Research
Ábhair:
Rochtain ar líne:https://www.frontiersin.org/articles/10.3389/fpain.2022.872587/full