Vanadate impedes adipogenesis in mesenchymal stem cells derived from different depots within bone.
Glucocorticoid induced osteoporosis (GIO) is associated with an increase in bone marrow adiposity which skews the differentiation of mesenchymal stem cell (MSC) progenitors away from osteoblastogenesis and towards adipogenesis. We have previously found that vanadate, a non-specific protein tyrosine...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2016-08-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00108/full |