A two-dimensional model of the colonic crypt accounting for the role of the basement membrane and pericryptal fibroblast sheath.
The role of the basement membrane is vital in maintaining the integrity and structure of an epithelial layer, acting as both a mechanical support and forming the physical interface between epithelial cells and the surrounding connective tissue. The function of this membrane is explored here in the c...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
|
| Series: | PLoS Computational Biology |
| Online Access: | http://europepmc.org/articles/PMC3359972?pdf=render |