A Novel miRNA Screen Identifies miRNA-4454 as a Candidate Biomarker for Ventricular Fibrosis in Patients with Hypertrophic Cardiomyopathy

A Novel miRNA Screen Identifies miRNA-4454 as a Candidate Biomarker for Ventricular Fibrosis in Patients with Hypertrophic Cardiomyopathy

(1) Background: Left ventricular hypertrophy, myocardial disarray and interstitial fibrosis are the hallmarks of hypertrophic cardiomyopathy (HCM). Access to the myocardium for diagnostic purposes is limited. Circulating biomolecules reflecting the myocardial disease processes could improve the earl...

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Bibliographic Details
Main Authors: Tilo Thottakara, Natalie Lund, Elisabeth Krämer, Paulus Kirchhof, Lucie Carrier, Monica Patten
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biomolecules
Subjects:
circulating miRNA
biomarker
ventricular hypertrophy
hypertrophic cardiomyopathy
cardiac fibrosis
Online Access:https://www.mdpi.com/2218-273X/11/11/1718

Internet

https://www.mdpi.com/2218-273X/11/11/1718

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