Functional Elucidation of Nemopilema nomurai and Cyanea nozakii Nematocyst Venoms’ Lytic Activity Using Mass Spectrometry and Zymography

Functional Elucidation of Nemopilema nomurai and Cyanea nozakii Nematocyst Venoms’ Lytic Activity Using Mass Spectrometry and Zymography

Background: Medusozoans utilize explosively discharging penetrant nematocysts to inject venom into prey. These venoms are composed of highly complex proteins and peptides with extensive bioactivities, as observed in vitro. Diverse enzymatic toxins have been putatively identified in the venom of jell...

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Bibliographic Details
Main Authors: Yang Yue, Huahua Yu, Rongfeng Li, Ronge Xing, Song Liu, Kecheng Li, Xueqin Wang, Xiaolin Chen, Pengcheng Li
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Toxins
Subjects:
zymography
LC-MS/MS
enzymatic toxins
hemolysis
jellyfish metalloproteinase inhibitors
PLA2 inhibitors
Nemopilema nomurai
Cyanea nozakii
Online Access:http://www.mdpi.com/2072-6651/9/2/47

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http://www.mdpi.com/2072-6651/9/2/47

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