Apigenin attenuates high-fat diet-induced nephropathy in rats by hypoglycemic and hypolipidemic effects, and concomitant activation of the Nrf2/antioxidant axis
This study examined the protective potential of apigenin in rats with high-fat diet (HFD)-induced nephropathy, and tested its involvement in the activation of nuclear factor-erythroid 2 related factor 2 (Nrf2). Control, apigenin, HFD, HFD + apigenin, and HFD + Nrf2 inhibitor (brusatol) groups were f...
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| Format: | Article |
| Language: | English |
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Elsevier
2022-12-01
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| Series: | Journal of Functional Foods |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1756464622003656 |