Proximal tubule-derived exosomes contribute to mesangial cell injury in diabetic nephropathy via miR-92a-1-5p transfer

Proximal tubule-derived exosomes contribute to mesangial cell injury in diabetic nephropathy via miR-92a-1-5p transfer

Plain English Summary Diabetic nephropathy (DN) has been the leading cause of end-stage renal disease worldwide. Exosomes play a principle role in cross-talk of kidney cells and further affect the onset or progression of DN. This study firstly demonstrated the communication between proximal tubular...

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Bibliographic Details
Main Authors: Yi-Chun Tsai, Mei-Chuan Kuo, Wei-Wen Hung, Ping-Hsun Wu, Wei-An Chang, Ling-Yu Wu, Su-Chu Lee, Ya-Ling Hsu
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cell Communication and Signaling
Subjects:
Exosome
miR-92a-1-5p
Mesangial cell
Proximal tubular epithelial cell
Myofibroblast transdifferentiation
ER stress
Online Access:https://doi.org/10.1186/s12964-022-00997-y

Internet

https://doi.org/10.1186/s12964-022-00997-y

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