PI3K inhibitors in thrombosis and cardiovascular disease

PI3K inhibitors in thrombosis and cardiovascular disease

Abstract Phosphoinositide 3-kinases (PI3Ks) are lipid kinases that regulate important intracellular signalling and vesicle trafficking events via the generation of 3-phosphoinositides. Comprising eight core isoforms across three classes, the PI3K family displays broad expression and function through...

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Bibliographic Details
Main Authors: Tom N. Durrant, Ingeborg Hers
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical and Translational Medicine
Subjects:
Cardiovascular disease
Thrombosis
Platelets
Phosphoinositide 3-kinase
PI3K
Phosphoinositides
Online Access:http://link.springer.com/article/10.1186/s40169-020-0261-6

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http://link.springer.com/article/10.1186/s40169-020-0261-6

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