Comparison of LC-MS/MS and EMIT methods for the precise determination of blood sirolimus in children with vascular anomalies
Sirolimus (SRL) is a mammalian target of rapamycin (mTOR) inhibitor. The whole blood concentration of SRL is routinely monitored to tailor dosage and prevent toxicity. Currently, the enzyme multiplied immunoassay technique (EMIT) is often applied to perform therapeutic drug monitoring (TDM) of SRL,...
| Main Authors: | , , , , , , , |
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| 格式: | 文件 |
| 语言: | English |
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Frontiers Media S.A.
2022-09-01
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| 丛编: | Frontiers in Pharmacology |
| 主题: | |
| 在线阅读: | https://www.frontiersin.org/articles/10.3389/fphar.2022.925018/full |