NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription

NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription

Myosin VI (MVI) is known to interact with RNA Polymerase II and to play non-cytoplasmic roles in cells. Here, the authors provide evidence that the transcription co-activator NDP52 regulates MVI binding to DNA and that MVI interacts with nuclear receptors to drive gene expression.

Bibliographic Details
Main Authors: Natalia Fili, Yukti Hari-Gupta, Ália dos Santos, Alexander Cook, Simon Poland, Simon M. Ameer-Beg, Maddy Parsons, Christopher P. Toseland
Format: Article
Language:English
Published: Nature Portfolio 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-02050-w

Internet

https://doi.org/10.1038/s41467-017-02050-w

Similar Items