Primary Impacts of the Fungal Toxin Sporidesmin on HepG2 Cells: Altered Cell Adhesion without Oxidative Stress or Cell Death

Primary Impacts of the Fungal Toxin Sporidesmin on HepG2 Cells: Altered Cell Adhesion without Oxidative Stress or Cell Death

The fungal metabolite sporidesmin is responsible for severe necrotizing inflammation of biliary tract and liver of livestock grazing on pasture containing spores of <i>Pithomyces chartarum</i> that synthesizes the toxin. The toxin is secreted into bile causing the erosion of the biliary...

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Bibliographic Details
Main Authors: Magalie Boucher, T. William Jordan
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Toxins
Subjects:
cell adhesion
hepatobiliary injury
HepG2 cells
oxidative stress
sporidesmin
two-dimensional electrophoresis
Online Access:https://www.mdpi.com/2072-6651/13/3/179

Internet

https://www.mdpi.com/2072-6651/13/3/179

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