Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modulates expression of prognosis biomarkers of the disease

Intramuscular transplantation of bone marrow cells prolongs the lifespan of SOD1G93A mice and modulates expression of prognosis biomarkers of the disease

Abstract Background Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive muscle weakness, paralysis and death. There is no effective treatment for ALS and stem cell therapy has arisen as a potential therapeutic approach. Methods SOD1 mutant mice were used...

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Bibliographic Details
Main Authors: Amaya Rando, Diego Pastor, Mari Carmen Viso-León, Anna Martínez, Raquel Manzano, Xavier Navarro, Rosario Osta, Salvador Martínez
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Stem Cell Research & Therapy
Online Access:http://link.springer.com/article/10.1186/s13287-018-0843-z

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http://link.springer.com/article/10.1186/s13287-018-0843-z

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