RNA interference targeting NOX4 protects visual function in an experimental model of retinal detachment by alleviating blood-retinal barrier damage

AIM: To observe the effects of the inhibition of NADPH oxidase 4 (NOX4) expression on the retinal vascular barriers and visual function after retinal detachment (RD). METHODS: RD model was established 3wk after adeno-associaned virus vector injection. The retinal tissue was harvested 3d after RD, an...

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Bibliographic Details
Main Authors: Kai Dong, Nan Yang, Jie Ding, Yuan-Ye Yan, Li Lu, Yi-Sai Wang
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2021-01-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2021/1/20210107.pdf