A Comprehensive Comparison of Normalization Methods for Loading Control and Variance Stabilization of Reverse-Phase Protein Array Data

Loading control (LC) and variance stabilization of reverse-phase protein array (RPPA) data have been challenging mainly due to the small number of proteins in an experiment and the lack of reliable inherent control markers. In this study, we compare eight different normalization methods for LC and v...

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Bibliographic Details
Main Authors: Wenbin Liu, Zhenlin Ju, Yiling Lu, Gordon B. Mills, Rehan Akbani
Format: Article
Language:English
Published: SAGE Publishing 2014-01-01
Series:Cancer Informatics
Online Access:https://doi.org/10.4137/CIN.S13329