A Comprehensive Comparison of Normalization Methods for Loading Control and Variance Stabilization of Reverse-Phase Protein Array Data
Loading control (LC) and variance stabilization of reverse-phase protein array (RPPA) data have been challenging mainly due to the small number of proteins in an experiment and the lack of reliable inherent control markers. In this study, we compare eight different normalization methods for LC and v...
Main Authors: | Wenbin Liu, Zhenlin Ju, Yiling Lu, Gordon B. Mills, Rehan Akbani |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2014-01-01
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Series: | Cancer Informatics |
Online Access: | https://doi.org/10.4137/CIN.S13329 |
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