Overcoming resistance to immunotherapy by targeting GPR84 in myeloid-derived suppressor cells

Abstract Myeloid-derived suppressor cells (MDSCs) were found to gradually accumulate in the orthotopic esophageal cancer mouse model during tumor progression. Although the roles of MDSCs in promoting tumor growth and inhibiting immune response have been extensively explored, currently, there are sti...

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Bibliographic Details
Main Authors: Guohui Qin, Shasha Liu, Jinyan Liu, Hongwei Hu, Li Yang, Qitai Zhao, Congcong Li, Bin Zhang, Yi Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2023-04-01
Series:Signal Transduction and Targeted Therapy
Online Access:https://doi.org/10.1038/s41392-023-01388-6