Tollip or not Tollip: what are the evolving questions behind it?

Tollip plays an important role in the interleukin-1 receptor IL-1R and Toll pathways. As a modulator of the immune pathway, it indirectly controls the amount of antimicrobial peptides. This could indicate a vital step in maintaining animal immune systems and preventing infection. Evolutionary questi...

Full description

Bibliographic Details
Main Authors: Denis Prudencio Luiz, Célio Dias Santos Júnior, Ana Maria Bonetti, Malcom Antônio Manfredi Brandeburgo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24828816/pdf/?tool=EBI