Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution

Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution

Electron cryo-microscopy (cryo-EM) has emerged as a powerful method by which to obtain three-dimensional (3D) structures of macromolecular complexes at atomic or near-atomic resolution. However, de novo building of atomic models from near-atomic resolution (3–5 Å) cryo-EM density maps is a challengi...

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Bibliographic Details
Main Authors: Guillaume Bouvier, Benjamin Bardiaux, Riccardo Pellarin, Chiara Rapisarda, Michael Nilges
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Biomolecules
Subjects:
cryo-EM
co-evolution
model building
minimum spanning tree
type 6 secretion system
Online Access:https://www.mdpi.com/2218-273X/12/9/1290

Internet

https://www.mdpi.com/2218-273X/12/9/1290

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