Disrupted Peyer’s Patch Microanatomy in COVID-19 Including Germinal Centre Atrophy Independent of Local Virus

Disrupted Peyer’s Patch Microanatomy in COVID-19 Including Germinal Centre Atrophy Independent of Local Virus

Confirmed SARS-coronavirus-2 infection with gastrointestinal symptoms and changes in microbiota associated with coronavirus disease 2019 (COVID-19) severity have been previously reported, but the disease impact on the architecture and cellularity of ileal Peyer’s patches (PP) remains unknown. Here w...

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Bibliographic Details
Main Authors: Silvia C. Trevelin, Suzanne Pickering, Katrina Todd, Cynthia Bishop, Michael Pitcher, Jose Garrido Mesa, Lucia Montorsi, Filomena Spada, Nedyalko Petrov, Anna Green, Manu Shankar-Hari, Stuart J.D. Neil, Jo Spencer
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
germinal centre
Peyer’s patches
atrophy of lymphoid follicle
gut Sars-Cov2 infection
severe COVID-19
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.838328/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.838328/full

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