Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients.

Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients.

BACKGROUND: Recent studies have suggested that deregulated AKT1 signaling is associated with schizophrenia. We hypothesized that if this is indeed the case, we should observe both decreased AKT1 expression as well as deregulation of AKT1 regulated pathways in Peripheral Blood Mononuclear Cells (PBMC...

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Bibliographic Details
Main Authors: Nico J M van Beveren, Gabrielle H S Buitendijk, Sigrid Swagemakers, Lianne C Krab, Christian Röder, Lieuwe de Haan, Peter van der Spek, Ype Elgersma
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3290567?pdf=render

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http://europepmc.org/articles/PMC3290567?pdf=render

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