Circulating Angiotensin-(1–7) Is Reduced in Alzheimer’s Disease Patients and Correlates With White Matter Abnormalities: Results From a Pilot Study

Circulating Angiotensin-(1–7) Is Reduced in Alzheimer’s Disease Patients and Correlates With White Matter Abnormalities: Results From a Pilot Study

IntroductionAlzheimer’s disease (AD) is the leading cause of dementia worldwide. Despite the extensive research, its pathophysiology remains largely unelucidated. Currently, more attention is being given to the disease’s vascular and inflammatory aspects. In this context, the renin-angiotensin syste...

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Bibliographic Details
Main Authors: Victor Teatini Ribeiro, Thiago Macedo e Cordeiro, Roberta da Silva Filha, Lucas Giandoni Perez, Paulo Caramelli, Antônio Lúcio Teixeira, Leonardo Cruz de Souza, Ana Cristina Simões e Silva
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
renin angiotensin system
Angiotensin-(1–7)
angiotensin II
white matter hypointensities
cerebrovascular lesions
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.636754/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.636754/full

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