Microglia activated by microbial neuraminidase contributes to ependymal cell death
Abstract The administration of microbial neuraminidase into the brain ventricular cavities of rodents represents a model of acute aseptic neuroinflammation. Ependymal cell death and hydrocephalus are unique features of this model. Here we demonstrate that activated microglia participates in ependyma...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Fluids and Barriers of the CNS |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12987-021-00249-0 |