Microglia activated by microbial neuraminidase contributes to ependymal cell death

Abstract The administration of microbial neuraminidase into the brain ventricular cavities of rodents represents a model of acute aseptic neuroinflammation. Ependymal cell death and hydrocephalus are unique features of this model. Here we demonstrate that activated microglia participates in ependyma...

Full description

Bibliographic Details
Main Authors: María del Mar Fernández-Arjona, Ana León-Rodríguez, María Dolores López-Ávalos, Jesús M. Grondona
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:https://doi.org/10.1186/s12987-021-00249-0