Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma

Multimodal molecular landscape of response to Y90-resin microsphere radioembolization followed by nivolumab for advanced hepatocellular carcinoma

Background Combination therapy with radioembolization (yttrium-90)-resin microspheres) followed by nivolumab has shown a promising response rate of 30.6% in a Phase II trial (CA209-678) for advanced hepatocellular carcinoma (HCC); however, the response mechanisms and relevant biomarkers remain unkno...

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Bibliographic Details
Main Authors: David Tai, Fei Yao, Joycelyn Lee, Su Pin Choo, Joe Yeong, Jeffrey Chun Tatt Lim, Han Chong Toh, Xinru Lim, Jiangfeng Ye, Denise Goh, Tony Kiat-Hon Lim, Mai Chan Lau, Timothy Wai Ho Shuen, Weiwei Zhai, Jia Qi Lim, Lawrence Cheung, Neslihan Arife Kaya, Cheryl Zi Jin Phua, Felicia Yu Ting Wee, Craig Ryan Joseph, Zhen Wei Neo, Kelvin S H Loke, Apoorva Gogna, May Yin Lee, Axel Hilmer, Yun Shen Chan, Wai Leong Tam
Format: Article
Language:English
Published: BMJ Publishing Group 2023-08-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/11/8/e007106.full

Internet

https://jitc.bmj.com/content/11/8/e007106.full

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