Sodium Imbalance in Mice Results Primarily in Compensatory Gene Regulatory Responses in Kidney and Colon, but Not in Taste Tissue

Sodium Imbalance in Mice Results Primarily in Compensatory Gene Regulatory Responses in Kidney and Colon, but Not in Taste Tissue

Renal excretion and sodium appetite provide the basis for sodium homeostasis. In both the kidney and tongue, the epithelial sodium channel (ENaC) is involved in sodium uptake and sensing. The diuretic drug amiloride is known to block ENaC, producing a mild natriuresis. However, amiloride is further...

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Bibliographic Details
Main Authors: Kristina Lossow, Wolfgang Meyerhof, Maik Behrens
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Nutrients
Subjects:
epithelial sodium channel
sodium homeostasis
amiloride
salt deprivation
short-term preference test
Online Access:https://www.mdpi.com/2072-6643/12/4/995

Internet

https://www.mdpi.com/2072-6643/12/4/995

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