Copper as a Collaborative Partner of Zinc-Induced Neurotoxicity in the Pathogenesis of Vascular Dementia

Copper as a Collaborative Partner of Zinc-Induced Neurotoxicity in the Pathogenesis of Vascular Dementia

Copper is an essential trace element and possesses critical roles in various brain functions. A considerable amount of copper accumulates in the synapse and is secreted in neuronal firings in a manner similar to zinc. Synaptic copper and zinc modulate neuronal transmission and contribute to informat...

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Bibliographic Details
Main Authors: Masahiro Kawahara, Ken-ichiro Tanaka, Midori Kato-Negishi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
zinc
endoplasmic reticulum
MAP kinase
calcium homeostasis
mitochondria
synapse
Online Access:https://www.mdpi.com/1422-0067/22/14/7242

Internet

https://www.mdpi.com/1422-0067/22/14/7242

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