Next Generation Sequencing Detects Premeiotic Errors in Human Oocytes

Next Generation Sequencing Detects Premeiotic Errors in Human Oocytes

Autosomal aneuploidy is the leading cause of embryonic and foetal death in humans. This arises mainly from errors in meiosis I or II of oogenesis. A largely ignored source of error stems from germinal mosaicism, which leads to premeiotic aneuploidy. Molecular cytogenetic studies employing metaphase...

Full description

Bibliographic Details
Main Authors: Harita Ghevaria, Sioban SenGupta, Roy Naja, Rabi Odia, Holly Exeter, Paul Serhal, Xavier Viñals Gonzalez, Xuhui Sun, Joy Delhanty
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
human oocytes
premeiotic aneuploidy
meiosis
metaphase II oocyte and first polar body complex
next generation sequencing
Online Access:https://www.mdpi.com/1422-0067/23/2/665

Internet

https://www.mdpi.com/1422-0067/23/2/665

Similar Items