Vaccination of C57BL/10 mice against cutaneous leishmaniasis using killed promastigotes of different strains and species of Leishmania Vacinação de camundongos C57BL/10 contra leishmaniose com promastigotas mortas de diferentes cepas e espécies de Leishmania

Vaccination of C57BL/10 mice against cutaneous leishmaniasis using killed promastigotes of different strains and species of Leishmania Vacinação de camundongos C57BL/10 contra leishmaniose com promastigotas mortas de diferentes cepas e espécies de Leishmania

Antigenic extracts from five Leishmania stocks were used to vaccinate C57BL/10 mice. The Leishvacin® and PH8 monovalent vaccine yielded the highest IFN-gamma levels in the supernatants of spleen cell culture from vaccinated animals. Each single strain immunized group showed evidence of protective im...

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Bibliographic Details
Main Authors: Wilson Mayrink, Gilmara Cristina dos Santos, Vicente de Paulo Coelho Peixoto de Toledo, Tânia Mara Pinto Dabés Guimarães, George Luis Lins Machado-Coelho, Odair Genaro, Carlos Alberto da Costa
Format: Article
Language:English
Published: Sociedade Brasileira de Medicina Tropical (SBMT) 2002-04-01
Series:Revista da Sociedade Brasileira de Medicina Tropical
Subjects:
Leishmania
Vacina
Interferon-g
Interleucina-4
Vaccine
Interferon-gamma
Interleukin-4
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000200001

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822002000200001

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