Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation

Histone Deacetylase Inhibitors Impair Glioblastoma Cell Motility and Proliferation

Despite being subjected to high-dose chemo and radiotherapy, glioblastoma (GBM) patients still encounter almost inevitable relapse, due to the capability of tumor cells to disseminate and invade normal brain tissues. Moreover, the presence of a cancer stem cell (CSC) subpopulation, already demonstra...

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Bibliographic Details
Main Authors: Elena Rampazzo, Lorenzo Manfreda, Silvia Bresolin, Alice Cani, Elena Mariotto, Roberta Bortolozzi, Alessandro Della Puppa, Giampietro Viola, Luca Persano
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cancers
Subjects:
glioblastoma
histone deacetylase inhibitors
Wnt signaling
cell migration
interferon pathway
Online Access:https://www.mdpi.com/2072-6694/14/8/1897

Internet

https://www.mdpi.com/2072-6694/14/8/1897

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