Long-term social isolation stress exacerbates sex-specific neurodegeneration markers in a natural model of Alzheimer’s disease

Long-term social isolation stress exacerbates sex-specific neurodegeneration markers in a natural model of Alzheimer’s disease

Social interactions have a significant impact on health in humans and animal models. Social isolation initiates a cascade of stress-related physiological disorders and stands as a significant risk factor for a wide spectrum of morbidity and mortality. Indeed, social isolation stress (SIS) is indicat...

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Bibliographic Details
Main Authors: Carolina A. Oliva, Matías Lira, Claudia Jara, Alejandra Catenaccio, Trinidad A. Mariqueo, Carolina B. Lindsay, Francisco Bozinovic, Grisel Cavieres, Nibaldo C. Inestrosa, Cheril Tapia-Rojas, Daniela S. Rivera
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Aging Neuroscience
Subjects:
Octodon degus
social isolation stress
Amyloid-β protein
tau protein
inflammation
oxidative stress
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1250342/full

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https://www.frontiersin.org/articles/10.3389/fnagi.2023.1250342/full

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