S100B Secretion in Astrocytes, Unlike C6 Glioma Cells, Is Downregulated by Lactate

S100B is a calcium-binding protein produced and secreted by astrocytes in response to various extracellular stimuli. C6 glioma cells are a lineage commonly employed for astroglial studies due to the expression of astrocyte specific markers and behavior. However, in high-glucose medium, C6 S100B secr...

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Bibliographic Details
Main Authors: Nicholas Guerini Selistre, Leticia Rodrigues, Barbara Carolina Federhen, Vitor Gayger-Dias, Jéssica Taday, Krista Mineia Wartchow, Carlos-Alberto Gonçalves
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/14/1/7