Junctional ER Organization Affects Mechanotransduction at Cadherin-Mediated Adhesions

Cadherin-mediated adhesions (also known as adherens junctions) are adhesive complexes that connect neighboring cells in a tissue. While the role of the actin cytoskeleton in withstanding tension at these sites of contact is well documented, little is known about the involvement of microtubules and t...

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Bibliographic Details
Main Authors: Michelle Joy-Immediato, Manuel J. Ramirez, Mauricio Cerda, Yusuke Toyama, Andrea Ravasio, Pakorn Kanchanawong, Cristina Bertocchi
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.669086/full