Intravitreal Application: Physicochemical Properties of Drugs Dissolved in Silicone Oils of Different Density in Comparison to the Porcine Vitreous Body

Silicone oil endotamponades provide a reservoir for drugs in the eye. Following vitrectomy surgery to treat retinal detachments, extensive diabetic retinopathy or endophthalmitis, they can be used as long-term lipophilic depots. This study aimed to investigate the physicochemical properties of intra...

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Bibliographic Details
Main Authors: Maximilian Hammer, Sonja K. Schickhardt, Patrick R. Merz, Ramin Khoramnia, Alexander F. Scheuerle, Walter Mier, Philipp Uhl, Gerd U. Auffarth
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/7/1364