Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment

Chemo-enzymatic modification of poly-N-acetyllactosamine (LacNAc) oligomers and N,N-diacetyllactosamine (LacDiNAc) based on galactose oxidase treatment

The importance of glycans in biological systems is highlighted by their various functions in physiological and pathological processes. Many glycan epitopes on glycoproteins and glycolipids are based on N-acetyllactosamine units (LacNAc; Galβ1,4GlcNAc) and often present on extended poly-LacNAc glycan...

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Bibliographic Details
Main Authors: Christiane E. Kupper, Ruben R. Rosencrantz, Birgit Henßen, Helena Pelantová, Stephan Thönes, Anna Drozdová, Vladimir Křen, Lothar Elling
Format: Article
Language:English
Published: Beilstein-Institut 2012-05-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
chemo-enzymatic synthesis
galactose oxidase
glycosyltransferase
LacDiNAc
poly-N-acetyllactosamine
Online Access:https://doi.org/10.3762/bjoc.8.80

Internet

https://doi.org/10.3762/bjoc.8.80

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