Transcription factor E2F8 is a therapeutic target in the basal-like subtype of breast cancer

IntroductionTumorigenesis in breast cancers usually accompanied by the dysregulation of transcription factors (TFs). Abnormal amplification of TFs leads aberrant expression of its downstream target genes. However, breast cancers are heterogeneous disease with different subtypes that have distinguish...

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Bibliographic Details
Main Authors: Jing Zheng, Jingyi Huang, Jinquan Xia, Wenbin Zhou, Lingyun Dai, Sihang Lin, Lin Gao, Chang Zou
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Oncology
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Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1038787/full