Janus kinase V617F mutation detection in patients with myelofibrosis

Myelofibrosis (MF) is characterized by a presence of an extra fibrous tissue in the bone marrow and additional hematopoiesis. The somatic mutation in the Janus kinase 2 (JAK2) gene (V617F) occurs gradually and is detected in about 50.0% of myelofibrosis or essential thrombo-cytopenia (ET) patients....

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Bibliographic Details
Main Authors: Nikolova D, Yordanov A, Damyanova V, Radinov A, Toncheva D
Format: Article
Language:English
Published: Sciendo 2019-08-01
Series:Balkan Journal of Medical Genetics
Subjects:
Online Access:https://doi.org/10.2478/bjmg-2019-0007