Development of human alveolar epithelial cell models to study distal lung biology and disease

Development of human alveolar epithelial cell models to study distal lung biology and disease

Summary: Many acute and chronic diseases affect the distal lung alveoli. Alveolar epithelial cell (AEC) lines are needed to better model these diseases. We used de-identified human remnant transplant lungs to develop a method to establish AEC lines. The lines grow well in 2-dimensional (2D) culture...

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Bibliographic Details
Main Authors: Evelyn Tran, Tuo Shi, Xiuwen Li, Adnan Y. Chowdhury, Du Jiang, Yixin Liu, Hongjun Wang, Chunli Yan, William D. Wallace, Rong Lu, Amy L. Ryan, Crystal N. Marconett, Beiyun Zhou, Zea Borok, Ite A. Offringa
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:iScience
Subjects:
Cell biology
Stem cells research
Developmental biology
Transcriptomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222000505

Internet

http://www.sciencedirect.com/science/article/pii/S2589004222000505

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