Mucoadhesive formulation of Bidens pilosa L. (Asteraceae) reduces intestinal injury from 5-fluorouracil-induced mucositis in mice

Mucoadhesive formulation of Bidens pilosa L. (Asteraceae) reduces intestinal injury from 5-fluorouracil-induced mucositis in mice

Gastrointestinal mucositis induced during cancer treatment is considered a serious dose-limiting side effect of chemotherapy and/or radiotherapy. Frequently, interruption of the cancer treatment due to this pathology leads to a reduction in cure rates, increase of treatment costs and decrease life q...

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Bibliographic Details
Main Authors: Paulo Henrique Marcelino de Ávila, Renato Ivan de Ávila, Edvande Xavier dos Santos Filho, Carla Caroline Cunha Bastos, Aline Carvalho Batista, Elismauro Francisco Mendonça, Raphael Caixeta Serpa, Ricardo Neves Marreto, Andrezza Furquim da Cruz, Eliana Martins Lima, Marize Campos Valadares
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:Toxicology Reports
Subjects:
5-Fluorouracil
Bidens pilosa L. (Asteraceae)
Chemotherapy
Mucoadhesive formulation
Mucositis
Intestinal injury
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750015000359

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http://www.sciencedirect.com/science/article/pii/S2214750015000359

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