HER3 signaling and targeted therapy in cancer

ERBB family members including epidermal growth factor receptor (EGFR) also known as HER1, ERBB2/HER2/Neu, ERBB3/HER3 and ERBB4/HER4 are aberrantly activated in multiple cancers and hence serve as drug targets and biomarkers in modern precision therapy. The therapeutic potential of HER3 has long been...

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Bibliographic Details
Main Authors: Rosalin Mishra, Hima Patel, Samar Alanazi, Long Yuan, Joan T. Garrett
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Oncology Reviews
Subjects:
Online Access:http://www.oncologyreviews.org/index.php/or/article/view/355