The effects of meldonium on the acute ischemia/reperfusion liver injury in rats

The effects of meldonium on the acute ischemia/reperfusion liver injury in rats

Abstract Acute ischemia/reperfusion (I/R) liver injury is a clinical condition challenging to treat. Meldonium is an anti-ischemic agent that shifts energy production from fatty acid oxidation to less oxygen-consuming glycolysis. Thus, we investigated the effects of a 4-week meldonium pre-treatment...

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Bibliographic Details
Main Authors: Siniša Đurašević, Maja Stojković, Jelena Sopta, Slađan Pavlović, Slavica Borković-Mitić, Anđelija Ivanović, Nebojša Jasnić, Tomislav Tosti, Saša Đurović, Jelena Đorđević, Zoran Todorović
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-80011-y

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https://doi.org/10.1038/s41598-020-80011-y

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