The Pleiotropic Effects of the GM-CSF Rheostat on Myeloid Cell Differentiation and Function: More Than a Numbers Game

The Pleiotropic Effects of the GM-CSF Rheostat on Myeloid Cell Differentiation and Function: More Than a Numbers Game

Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) is a myelopoietic growth factor that has pleiotropic effects not only in promoting the differentiation of immature precursors into polymorphonuclear neutrophils (PMNs), monocytes/macrophages (MØs) and dendritic cells (DCs), but also in contro...

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Bibliographic Details
Main Authors: Yifan Zhan, Andrew M. Lew, Michael Chopin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
GM-CSF
macrophages
dendritic cells
differentiation
function
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02679/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02679/full

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