Effects of Chitosan Nanoparticles with Long Synthetic siRNAs Targeting VEGF in Triple-Negative Breast Cancer Cells

Effects of Chitosan Nanoparticles with Long Synthetic siRNAs Targeting VEGF in Triple-Negative Breast Cancer Cells

Abstract Vascular endothelial growth factor (VEGF) is an essential angiogenic factor in breast cancer development and metastasis. Small interfering RNAs (siRNAs) can specifically silence genes via the RNA interference pathway, therefore were investigated as cancer therapeutics. In this study, we inv...

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Bibliographic Details
Main Authors: Birnur Cömez, Jülide Akbuğa
Format: Article
Language:English
Published: Universidade de São Paulo 2023-06-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
siRNA
VEGF
Chitosan
Nanoparticle
Breast cancer
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100389&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502023000100389&tlng=en

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