Aggregative trans-eQTL analysis detects trait-specific target gene sets in whole blood

Large-scale genetic association studies have identified many trait-associated variants that influence gene expression. Here, the authors present ARCHIE, a tool for identifying sets of genes whose regulation may be related to specific complex traits.

Bibliographic Details
Main Authors: Diptavo Dutta, Yuan He, Ashis Saha, Marios Arvanitis, Alexis Battle, Nilanjan Chatterjee
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-31845-9