New anti-candida active nitrogen-containing bisphosphonates as inhibitors of farnesyl pyrophosphate synthase Candida albicans
In our previous work, a number of new nitrogen-containing bisphosphonates (N-BPs) with high predicted and experimental antifungal activity were presented as potential Candida albicans farnesyl pyrophosphate synthase (FPPS) inhibitors. To confirm this hypothesis, a homologous C. albicans FPPS model...
Principais autores: | , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2019-05-01
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coleção: | The Ukrainian Biochemical Journal |
Assuntos: | |
Acesso em linha: | http://ukrbiochemjournal.org/wp-content/uploads/2019/05/Metelytsia_3_19.pdf |