Adenovirus-mediated gene delivery restores fertility in congenitally infertile female mice

Oogenesis depends on close interactions between oocytes and granulosa cells. Abnormal signaling between these cell types can result in infertility. However, attempts to manipulate oocyte-granulosa cell interactions have had limited success, likely due to the blood-follicle barrier (BFB), which preve...

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Bibliographic Details
Main Authors: Mito KANATSU-SHINOHARA, Jiyoung LEE, Takehiro MIYAZAKI, Hiroko MORIMOTO, Takashi SHINOHARA
Format: Article
Language:English
Published: The Society for Reproduction and Development 2022-10-01
Series:The Journal of Reproduction and Development
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jrd/68/6/68_2022-090/_pdf/-char/en