Non-image-forming light driven functions are preserved in a mouse model of autosomal dominant optic atrophy.

Non-image-forming light driven functions are preserved in a mouse model of autosomal dominant optic atrophy.

Autosomal dominant optic atrophy (ADOA) is a slowly progressive optic neuropathy that has been associated with mutations of the OPA1 gene. In patients, the disease primarily affects the retinal ganglion cells (RGCs) and causes optic nerve atrophy and visual loss. A subset of RGCs are intrinsically p...

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Bibliographic Details
Main Authors: Georgia Perganta, Alun R Barnard, Christiana Katti, Athanasios Vachtsevanos, Ron H Douglas, Robert E MacLaren, Marcela Votruba, Sumathi Sekaran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3569441?pdf=render

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http://europepmc.org/articles/PMC3569441?pdf=render

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