Non-image-forming light driven functions are preserved in a mouse model of autosomal dominant optic atrophy.
Autosomal dominant optic atrophy (ADOA) is a slowly progressive optic neuropathy that has been associated with mutations of the OPA1 gene. In patients, the disease primarily affects the retinal ganglion cells (RGCs) and causes optic nerve atrophy and visual loss. A subset of RGCs are intrinsically p...
Asıl Yazarlar: | , , , , , , , |
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Materyal Türü: | Makale |
Dil: | English |
Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2013-01-01
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Seri Bilgileri: | PLoS ONE |
Online Erişim: | http://europepmc.org/articles/PMC3569441?pdf=render |