TNF-induced metalloproteinase-9 production is associated with neurological manifestations in HTLV-1-infected individuals

TNF-induced metalloproteinase-9 production is associated with neurological manifestations in HTLV-1-infected individuals

HTLV-1-infected individuals may develop a neurologic inflammatory condition known as HTLV-1-associated myelopathy (HAM/TSP), in which the high production of TNF is observed. These patients exhibit higher proviral loads, enhanced production of proinflammatory cytokines and lymphocyte proliferation in...

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Bibliographic Details
Main Authors: Mariele Guerra, Natália B. Carvalho, Silvane Santos, Mauricio T. Nascimento, Renata Sá, Augusto M. Carvalho, Edgar M. Carvalho, Lucas P. Carvalho
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
HTLV-1
HAM/TSP
metalloproteinases
TIMPs
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.954103/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.954103/full

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