TIGIT Expression on Intratumoral Lymphocytes Correlates with Improved Prognosis in Oral Squamous Cell Carcinoma

TIGIT Expression on Intratumoral Lymphocytes Correlates with Improved Prognosis in Oral Squamous Cell Carcinoma

(1) Background: T-cell immunoglobulin and ITIM domain (TIGIT) is a potential immunotherapeutic target in a variety of malignant entities, and antibody-based treatments are currently under investigation in clinical trials. While promising results were observed in patients with lung cancer, the role o...

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Bibliographic Details
Main Authors: Jonas Eichberger, Silvia Spoerl, Gerrit Spanier, Ramona Erber, Juergen Taxis, Johannes Schuderer, Nils Ludwig, Mathias Fiedler, Felix Nieberle, Tobias Ettl, Carol I. Geppert, Torsten E. Reichert, Steffen Spoerl
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Biomedicines
Subjects:
T-cell immunoglobulin and ITIM domain (TIGIT)
programmed death-ligand 1 (PD-L1)
head and neck squamous cell carcinoma (HNSCC)
oral squamous cell carcinoma (OSCC)
immune checkpoint
immunotherapy
Online Access:https://www.mdpi.com/2227-9059/10/12/3236

Internet

https://www.mdpi.com/2227-9059/10/12/3236

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